As the COVID-19 pandemic shows little signs of abating, pharmaceutical firms, life-science companies and healthcare authorities are racing to learn more about this dangerous virus and develop a cure/vaccine. These efforts include collecting mass amounts of data and disseminating important information as thoroughly and quickly as possible.

 

We have augmented HOLMES Assistant for Researcher with a domain-contextual offering for COVID-19 inquiries. This addition allows vaccine researchers to search COVID-19 articles using advanced Natural-Language Understanding (NLU) models built with deep learning, enabling them to uncover specific paragraphs relevant to their query. Examples are below.

 

The core AI model has been trained on 30 million biomedical research publications, while the AI-based search engine has been tested and tuned with more than 19,000 research articles on COVID-19. HOLMES itself already has use-cases in Adverse Event reporting and Product Compliance Management, which can be leveraged when a potential cure for COVID-19 is discovered.

 

HOLMES BioMed Semantic Search is an information extraction solution that performs semantic retrieval from the knowledge article corpus. The solution uses NLU models to understand and extract information from hundreds of thousands of text articles. This AI-based search engine can be also be trained in other domains that have a corpus of text documents that are heavy on domain-specific terminology. Mindful that COVID-19 research (and other topics) are a global concern, this solution is also multilingual.

 

HOLMES Researcher assistant uses a persistent index so the most relevant information can be extracted quickly. Here are some of sample queries:

 

Query 1: “Japanese health recommendations on gargling to prevent respiratory infections”

Bot:

CONFIDENCE: 0.714

TITLE: Gargling for Oral Hygiene and the Development of Fever in Childhood: A Population Study in Japan

ABSTRACT: Background: Fever is one of the most common symptoms….

 

CONFIDENCE: 0.591

TITLE: Visibility and transmission: complexities around promoting hand hygiene in young children — a qualitative study

ABSTRACT: Background: Effective hand hygiene practice can reduce transmission of diseases….

 

 

Query 2: “Impact of Porcine reproductive and respiratory syndrome (PRRS) on American swine industry”

Bot:

CONFIDENCE: 0.824

TITLE: Identification of serum proteomic biomarkers for early porcine reproductive and respiratory syndrome (PRRS) infection

ABSTRACT: Background: Porcine reproductive and respiratory syndrome (PRRS) is one of the most significant swine diseases worldwide….

 

CONFIDENCE: 0.815

TITLE: Molecules Evaluation of the Inhibitory Effects of (E)-1-(2-hydroxy-4,6-dimethoxyphenyl)-3- (naphthalen-1-yl)prop-2-en-1-one (DiNap), a Natural Product Analog, on the Replication of Type 2 PRRSV In Vitro and In Vivo

ABSTRACT: DiNap [(E)-1-(2-hydroxy-4,6-dimethoxyphenyl)-3-(naphthalen-1-yl)prop-2-en-1-one], an analog of a natural product (the chalcone flavokawain), was synthesized and characterized in this study….

 

 

Query 3: “What are the historical synthesis of some disease outbreaks causally linked to bats”

Bot:

CONFIDENCE: 0.779

TITLE:  Bats and zoonotic viruses: can we confidently link bats with emerging deadly viruses?

ABSTRACT: An increasingly asked question is ‘can we confidently link bats with emerging viruses? …..

 

CONFIDENCE: 0.606

TITLE:  Bat Distribution Size or Shape as Determinant of Viral Richness in African Bats

ABSTRACT: The rising incidence of emerging infectious diseases (EID) is mostly linked to biodiversity loss, changes in habitat use and increasing habitat fragmentation….

 

Using HOLMES Assistant for Researcher, professionals from the pharmaceutical, life-science and healthcare sectors can quickly review thousands of documents for data that may accelerate their discovery of a vaccine or cure for COVID-19.

Varadharajan S

Varadharajan S

General Manger, Global Presales Head, Wipro HOLMES

@WiproDigital

Varadha and his team collaborate with leading companies across industries to deliver AI-powered automation using Wipro HOLMES and third-party ecosystem solutions to automate business, application and infrastructure operations and transformation initiatives. With over two decades of experience in delivery, presales, practice development and client relationship management, Varadha specializes in shaping new offerings and driving outcome-based solutions across industry verticals.

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